A4685

Luminol sodium salt

luminescent, ≥98% (titration), powder and chunks

• Synonyme(s) : 3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione
• Formule linéaire : C₈H₆N₃O₂Na
• Numéro CAS: 20666-12-0
• Poids moléculaire : 199.14
• Numéro MDL: MFCD00161491
• Code UNSPSC : 12352204
• ID de substance PubChem : 24890898
• Nomenclature NACRES : NA.83

Propriétés

• product name: Luminol sodium salt,
• Pureté: ≥98% (titration)
• Forme: powder and chunks
• Solubilité: water: 50 mg/mL, clear to very slightly hazy, colorless to faint red
• Chaîne SMILES: O=C1NN([Na])C(C2=CC=CC(N)=C21)=O
• InChI: 1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1
• Clé InChI: RVJVDCVIJCBUTH-UHFFFAOYSA-M

Description

Application

Luminol sodium salt has been used:

• as a component of MEBSS buffer in a bioluminescence assay to detect peroxidase activity in whole blood samples
• to study protein interaction in whole-cell lysates by immunoprecipitation
• for in vitro reactive oxygen species (ROS) quantification in CD45⁺ and CD45− cells

Actions biochimiques/physiologiques

Luminol is a redox-sensitive chemiluminescent compound. It emits blue luminescence when the basic aqueous solution of luminol having oxygen atoms come in contact with oxidizing agents like potassium ferricyanide. It is highly stable and is applicable in various fields such as analytical chemistry, metallurgy, biochemistry, and forensics for detecting reactive species. Luminol has the potential to detect defects in neutrophils ex vivo during oxidative metabolism defects such as chronic granulomatous disease and myeloperoxidase deficiency.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves