11039

L-Arginine monohydrochloride

≥99.5% (AT), suitable for ligand binding assays, BioUltra

• Synonyme(s) : (S)-(+)-Arginine hydrochloride
• Formule empirique (notation de Hill) : C₆H₁₄N₄O₂ · HCl
• Numéro CAS: 1119-34-2
• Poids moléculaire : 210.66
• NACRES: NA.26
• PubChem Substance ID: 57646880
• UNSPSC Code: 12352209
• EC Number: 214-275-1
• MDL number: MFCD00064550
• Beilstein/REAXYS Number: 3631658

Propriétés

• Nom du produit: L-Arginine monohydrochloride, BioUltra, ≥99.5% (AT)
• product line: BioUltra
• Quality Segment: 200
• assay: ≥99.5% (AT)
• form: powder or crystals
• optical activity: [α]20/D +22.0±0.5°, c = 5% in 5 M HCl
• technique(s): ligand binding assay: suitable
• impurities: insoluble matter, passes filter test, ≤0.3% foreign amino acids
• ign. residue: ≤0.05%
• loss: ≤0.05% loss on drying, 20 °C (HV)
• color: colorless or white
• pH: 5.5-7.0 (25 °C, 1 M in H₂O)
• mp: 220-230 °C
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• density: 1.42 g/cm³ at 20 °C
• anion traces: sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: ≤0.2, λ: 280 nm A_max: ≤0.1
• SMILES string: Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
• InChI key: KWTQSFXGGICVPE-WCCKRBBISA-N

Description

Application

L-Arginine monohydrochloride has been used to study the reversal of the inhibitory effect of L-N^G0-nitroarginine on non-cholinergic relaxations. It has also been used as a dietary supplement to study its effect on endothelium-dependent vasodilation.

Biochem/physiol Actions

L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development of kidney and cardiovascular disease. L-arginine is found to decrease fat mass and visceral adiposity.

Substrat de l′oxyde nitrique synthase qui est converti en citrulline et oxyde nitrique (NO). Induit la libération d′insuline par un mécanisme dépendant de l′oxyde nitrique.

Informations sur la sécurité

• Classe de stockage: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves