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07188

Sigma-Aldrich

Lithium mupirocin

≥95.0% (HPLC)

Synonyme(s) :

9-((E)-4-{(2S,3R,4R,5S)-3,4-Dihydroxy-5-[(2S,3S)-3-((1S,2S)-2-hydroxy-1-methyl-propyl)oxiranylmethyl]tetrahydro-pyran-2-yl}-3-methyl-but-2-enoyloxy)nonanoic acid lithium salt, Pseudomonic acid A lithium salt

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About This Item

Formule empirique (notation de Hill):
C26H43LiO9
Numéro CAS:
73346-79-9
Poids moléculaire :
506.56
Numéro MDL:
MFCD11977847
Code UNSPSC :
51102829
ID de substance PubChem :
329748364
Nomenclature NACRES :
NA.85

Pureté

≥95.0% (HPLC)

Forme

powder

Couleur

white to off-white

Spectre d'activité de l'antibiotique

Gram-positive bacteria

Mode d’action

protein synthesis | interferes

Chaîne SMILES 

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

Clé InChI

XFIKMPRBSORKQP-JATHGWPISA-M

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Application

Lithium mupirocin as been used to study mupirocin resistance in staphylococcus aureus and in mycoplasma susceptibility studies .

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Storage class (TRGS 510): Non Combustible Solids

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

P C Hannan
Journal of medical microbiology, 47(12), 1115-1122 (1998-12-18)
The susceptibilities of 40 strains of various Mycoplasma species to 10 classes of antimicrobial agents were compared in vitro by a broth microdilution method. The strains tested comprised 20 strains of four AIDS-associated species--M. penetrans (1 strain), M. fermentas (5
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Miranda M L van Rijen et al.
PloS one, 7(8), e43065-e43065 (2012-08-24)
A multi centre double-blind randomised-controlled trial (M-RCT), carried out in the Netherlands in 2005-2007, showed that hospitalised patients with S. aureus nasal carriage who were treated prophylactically with mupirocin nasal ointment and chlorhexidine gluconate medicated soap (MUP-CHX), had a significantly
Christine H Smith et al.
Canadian family physician Medecin de famille canadien, 58(12), 1350-1352 (2012-12-18)
I see otherwise healthy children in my practice with recurrent staphylococcal skin infections. While I am comfortable with managing each acute infection, what can be done to eradicate Staphylococcus aureus and reduce the chance of recurrent infections? Staphylococcus aureus skin
Yi-Yuan Chiu et al.
BMC genomics, 13 Suppl 7, S21-S21 (2013-01-11)
To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth of
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