PHR1342

Sucralose

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : 4-chloro-4-désoxy-α-D-galactose de 1,6-dichloro-1,6-didésoxy-β-D-fructofurannosyle, E955, Trichlorosucrose
• Formule empirique (notation de Hill): C₁₂H₁₉Cl₃O₈
• Numéro CAS: 56038-13-2
• Poids moléculaire : 397.63
• Numéro Beilstein : 3654410
• Numéro MDL: MFCD03648615
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823327
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to Ph. Eur. Y0001344; traceable to USP 1623626
• Famille d'API: sucralose
• CofA (certificat d'analyse): current certificate can be downloaded
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl
• InChI: 1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
• Clé InChI: BAQAVOSOZGMPRM-QBMZZYIRSA-N

Description

Description générale

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
Sucralose is a polar, chlorinated sugar synthesized from saccharose precursor. It is widely used as a sweetener in a number of food and beverage products.

Application

Sucralose may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Actions biochimiques/physiologiques

Un exhausteur de goût sucré de synthèse, détectable par l'être humain. Active les récepteurs du goût sucré T1R2/T1R3 sur les cellules entéroendocrines et déclenche une sécrétion hormonale accrue de glucagon-like peptide-1 (GLP-1) et de peptide insulinotrope dépendant du glucose (GIP).

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA1094 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable