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D0501

Supelco

4-Deoxypyridoxine hydrochloride

analytical standard

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About This Item

Formule empirique (notation de Hill):
C8H11NO2 · HCl
Numéro CAS:
148-51-6
Poids moléculaire :
189.64
Numéro CE :
205-714-8
Numéro MDL:
MFCD00051296
Code UNSPSC :
41116107
ID de substance PubChem :
329798615
Nomenclature NACRES :
NA.24

Source biologique

synthetic (organic)

Niveau de qualité

100

Qualité

analytical standard

Pureté

≥98%

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Couleur

white to yellow

Pf

263-265 °C

Application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

Cl.Cc1ncc(CO)c(C)c1O

InChI

1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H

Clé InChI

QZKKOQQIVLXUEI-UHFFFAOYSA-N

Description générale

4-Deoxypyridoxine hydrochloride is a strong antagonist of vitamin B6.

Application

4-Deoxypyridoxine hydrochloride analytical standard can be used as follows:
  • Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with mass spectrometric (MS) detection for the impurity analysis of metadoxine drug
  • As an internal standard in the ultra- and high- performance liquid chromatographic analysis of pyridoxine in multivitamin tablet samples coupled with UV, mass spectrometric, and fluorescence detector

Autres remarques

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
0000340997
0000340997
WXBF2787V
WXBF4770V
WXBF3938V

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Consulter la Bibliothèque de documents

J Scountzou et al.
Immunopharmacology and immunotoxicology, 11(4), 657-666 (1989-01-01)
We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (PHA)
HPLC analysis of vitamin B6 in foods
Ollilainen, V-M
Agricultural and food science, 8(6), 515-619 (1999)
A Trakatellis et al.
Postgraduate medical journal, 68 Suppl 1, S70-S77 (1992-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme was very low. Under the influence of mitogenic stimuli serine hydroxymethyl-transferase activity was induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine, a
S P Coburn et al.
The Journal of nutrition, 119(2), 181-188 (1989-02-01)
In previous work identification of urinary metabolites of 4'-deoxypyridoxine which had been oxidized in the 5'-position and long-term dilution of labeled urinary metabolites with unlabeled molecules suggested possible microbial contributions. In the current studies germfree guinea pigs were able to
V E Allgood et al.
The Journal of biological chemistry, 265(21), 12424-12433 (1990-07-25)
We have examined the influence of intracellular vitamin B6 concentration on glucocorticoid receptor function in HeLa S3 cells transfected with a glucocorticoid-responsive chloramphenicol acetyltransferase (CAT) reporter plasmid. CAT activity is induced from this plasmid specifically by glucocorticoid hormones in a
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