07260

6-Aminohexanoic acid

≥98.5% (NT)

• Synonyme(s) : 6-Aminocaproic acid, 6-ACA, Aca, Acp, Aha, Ahx, acikaprin, afibrin, amicar, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA
• Formule linéaire : H₂N(CH₂)₅CO₂H
• Numéro CAS: 60-32-2
• Poids moléculaire : 131.17
• Numéro Beilstein : 906872
• Numéro CE : 200-469-3
• Numéro MDL: MFCD00008238
• Code UNSPSC : 12352202
• ID de substance PubChem : 329748386
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 200
• Pureté: ≥98.5% (NT)
• Pf: 207-209 °C (dec.) (lit.)
• Chaîne SMILES: NCCCCCC(O)=O
• InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
• Clé InChI: SLXKOJJOQWFEFD-UHFFFAOYSA-N
• Informations sur le gène: human ... PLAT(5327) , PLG(5340)

Description

Description générale

6-Aminohexanoic acid, or 6-aminocaproic acid, acts as an inhibitor of serine proteases. It shares structural similarities with the natural amino acid lysine but lacks an α-amino group.

Application

6-Aminohexanoic acid has been used as a component of the growth medium for tenogenic differentiation of mesenchymal stem cells. It has also been used in the preparation of modified graphene quantum dots.

Actions biochimiques/physiologiques

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Autres remarques

Improves solubilization of membrane proteins in electrophoresis

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 404.6 - 408.2 °F
• Point d'éclair (°C): 207 - 209 °C
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves