SCT090
BioTracker Bacterial FtsZ Live Cell Dye
Synonyme(s) :
BioTracker Bacterial FtsZ Live Cell Dye
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About This Item
Code UNSPSC :
12352207
Nomenclature NACRES :
NA.47
Produits recommandés
Forme
lyophilized
Poids mol.
calculated mol wt 782.1
Conditionnement
pkg of 1 mg
Fabricant/nom de marque
Millipore
Conditions de stockage
protect from light
Mode de croissance
N/A
Conditions d'expédition
ambient
Température de stockage
−20°C
Description générale
The filamentous temperature-sensitive Z (FtsZ) protein is a promising target for the development of new antibacterial drug targets. FtsZ is a protein encoded by the ftsZ gene that assembles into a ring at the future site of bacterial cell division and is one of the most conserved proteins in prokaryotes. This live cell probe will aid development of new FtsZ inhibitors and enable screening for FtsZ inhibition in a broad range of bacterial species. BioTracker Bacterial FtsZ Live Cell Dye is a BODIPY conjugated fluorescent probe that binds FtsZ proteins from both Gram-positive pathogens (Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, Streptococcus pyogenes, Streptococcus agalactiae, and Streptococcus pneumoniae) and Gram-negative pathogens (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii) (1). It allows for visualization of FtsZ using fluorescence microscopy, and can be used to monitor and identify non-fluorescent FtsZ inhibitors in these target pathogens. Spectral PropertiesExcitation: 488 nmEmission: 510 nmReference:1. Ferrer-González, Edgar, et al. "Structure-Guided Design of a fluorescent probe for the Visualization of ftsZ in clinically important Gram-positive and Gram-negative Bacterial pathogens." Scientific reports 9.1 (2019): 1-16.
Application
Purity ≥ 98% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.
Caractéristiques et avantages
Fluorescence probe for detecting FtsZ in bacteria
Forme physique
Lyophilized. Red solid.
Stockage et stabilité
Store at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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