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07-548

Anti-monomethyl-Histone H3 (Lys36) Antibody

serum, Upstate®

Synonyme(s) :

H3K36me1, Histone H3 (mono methyl K36)

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
vertebrates
Application:
DB, IF, WB, multiplexing
Citations:
8
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biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

vertebrates

manufacturer/tradename

Upstate®

technique(s)

dot blot: suitable, immunofluorescence: suitable, multiplexing: suitable, western blot: suitable

isotype

IgG

NCBI accession no.

NM_003493

UniProt accession no.

Q16695

shipped in

wet ice

target post-translational modification

monomethylation (Lys36)

Gene Information

human ... H3F3B(3021)

General description

17kDa

Immunogen

Peptide containing the sequence GVmeKKP corresponding to monomethyl Lysine 36 of human histone H3 .

Application

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Use Anti-monomethyl-Histone H3 (Lys36) Antibody (Rabbit Polyclonal Antibody) validated in DB, IF, WB, Mplex to detect monomethyl-Histone H3 (Lys36) also known as H3K36me1, Histone H3 (monomethyl K36).

Biochem/physiol Actions

monomethyl-Histone H3 (Lys36)

Physical form

0.05% sodium azide and 30% glycerol
Antiserum

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot in chicken core histones

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Contenu apparenté

Shaping Epigenetics Discovery - Epigenetics Product Selection Brochure

"Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. These changes can be cell- or tissue-specific, and can be passed on to multiple generations. Epigenetic regulation enriches DNAbased information, allowing a cell to vary its response across diverse biological and environmental contexts. Although epigenetic mechanisms are primarily centered in the nucleus, these mechanisms can be induced by environmental signals such as hormones, nutrients, stress, and cellular damage, pointing to the involvement of cytoplasmic and extracellular factors in epigenetic regulation."

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.
Li, Yan, et al.
The Journal of Biological Chemistry, 284, 34283-34295 (2009)
Changhui Sun et al.
The Plant cell, 24(8), 3235-3247 (2012-08-16)
Chromatin modifications affect flowering time in the long-day plant Arabidopsis thaliana, but the role of histone methylation in flowering time regulation of rice (Oryza sativa), a short-day plant, remains to be elucidated. We identified a late-flowering long vegetative phase1 (lvp1)
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome.
Inagaki, S; Miura-Kamio, A; Nakamura, Y; Lu, F; Cui, X; Cao, X; Kimura, H; Saze, H; Kakutani, T
The Embo Journal null
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Numéro d'article de commerce international

RéférenceGTIN
07-54804053252409493