Product 724858, poly(N-isopropylacrylamide-co-methacrylic acid), is a random copolymer and is synthesized by a conventional radical polymerization route.
724858
Poly(N-isopropylacrylamide-co-methacrylic acid)
methacrylic acid 10 mol %, Mn 60,000
Synonyme(s) :
Poly(NIPAM-co-MAA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM
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About This Item
Formule linéaire :
(C6H11NO)m (C4H6O2)n
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23
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Forme
solid
Niveau de qualité
Poids mol.
Mn 60,000
Composition
methacrylic acid, 10 mol %
Pf
>300 °C
Mw/Mn
≤2.5
Chaîne SMILES
N(C(C)C)C(=O)C=C.OC(=O)C(=C)C
InChI
1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)
Clé InChI
BGJOTKHBFYMJST-UHFFFAOYSA-N
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Application
Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive materials.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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On the stability of insulin delivered through a new glucose-responsive polymeric composite membrane.
Kai Zhang et al.
The Journal of pharmacy and pharmacology, 56(5), 611-620 (2004-05-15)
A new glucose-responsive polymeric composite membrane that provided pulsatile insulin release was developed in our laboratory previously. To develop a clinically useful insulin delivery system, this study was designed to investigate factors influencing insulin stability during delivery by this membrane.
Yunlu Dai et al.
ACS nano, 6(4), 3327-3338 (2012-03-23)
In this study, we report a new controlled release system based on up-conversion luminescent microspheres of NaYF(4):Yb(3+)/Er(3+) coated with the smart hydrogel poly[(N-isopropylacrylamide)-co-(methacrylic acid)] (P(NIPAM-co-MAA)) (prepared using 5 mol % of MAA) shell. The hybrid microspheres show bright up-conversion fluorescence
Kai Zhang et al.
Biomacromolecules, 5(4), 1248-1255 (2004-07-13)
To elucidate the mechanism of stimuli-responsive permeability and to optimize the design, the nanostructure of polymeric composite membranes, developed in our laboratory, was characterized. The membranes were prepared to contain various amounts of stimuli-responsive nanoparticles of poly(N-isopropylacrylamide-co-methacrylic acid), with or
J Taillefer et al.
Journal of pharmaceutical sciences, 89(1), 52-62 (2000-02-09)
pH-responsive polymeric micelles (PM) consisting of random copolymers of N-isopropylacrylamide (NIPA), methacrylic acid (MAA), and octadecyl acrylate (ODA) were prepared and characterized. The critical aggregation concentration, as determined by a fluorescence probe technique, was approximately 10 mg/L in water and
O Meyer et al.
FEBS letters, 421(1), 61-64 (1998-02-14)
Stable liposomes were rendered pH-sensitive by complexation to a polymer that undergoes marked temperature- and pH-dependent water solubility changes. The N-isopropylacrylamide-methacrylic acid copolymer was prepared with or without octadecyl acrylate. At pH below the phase transition of the polymer, egg
Articles
Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.
Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.
By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.
By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.
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