1610001

Scopolamine hydrobromide

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (−)-Scopolamine hydrobromide trihydrate, Hyoscine hydrobromide, Scopine tropate
• Empirical Formula (Hill Notation): C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS Number: 6533-68-2
• Molecular Weight: 438.31
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751078
• MDL number: MFCD00150066
• Beilstein/REAXYS Number: 6100669

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: scopolamine, hyoscine
• manufacturer/tradename: USP
• mp: 195-199 °C (dry matter) (lit.)
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• SMILES string: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI key: LACQPOBCQQPVIT-SEYKEWMNSA-N
• Gene Information: human ... CHRM1(1128)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Scopolamine hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Belladonna Extract
• Belladonna Extract Tablets
• Belladonna Leaf
• Belladonna Tincture
• Homatropine Hydrobromide
• Methscopolamine Bromide
• Methscopolamine Bromide Tablets

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist.

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H300 + H310 + H330
• Precautionary Statements: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable