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Lactalbumin

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About This Item

CAS Number:

9013-90-5

UNSPSC Code:

12352202

EC Number:

232-750-1

NACRES:

NA.61

MDL number:

MFCD00130492

Biological source:

bovine

Form:

powder

Technique(s):

cell culture | insect: suitable

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Properties

biological source

bovine

Quality Segment

200

form

powder

technique(s)

cell culture | insect: suitable

UniProt accession no.

P00711

storage temp.

2-8°C

Gene Information

bovine ... LALBA(281894)

Description

General description

α-Lactalbumin is a small, globular, whey protein that has been found in all milk studied to date. It is a metalloprotein of approximately 14 kDa produced in the mammary glands.

Application

Lactalbumin has also been used in rearing anopheline mosquitoes.

α-Lactalbumin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.

Biochem/physiol Actions

α-Lactalbumin consists of a single polypeptide chain with 8 cysteines which form disulfide bridges. α-Lactalbumin binds several metal ions, including calcium, which is thought to play a role in the regeneration of native α-lactalbumin from the reduced, denatured form. α-Lactalbumin also has a distinct zinc binding site that is thought to play a role in the binding of the lactose synthase complex. The mature protein consists of 123 amino acid residues (14 kDa), and it has a three-dimensional structure with 1.7 Angstrom resolution, demonstrating four a-helices and a triple stranded antiparallel β-sheet.

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This Item	L4385	L5385	L6010
Sigma-Aldrich L7252 Lactalbumin	Sigma-Aldrich L4385 α-Lactalbumin from bovine milk	Sigma-Aldrich L5385 α-Lactalbumin from bovine milk	Sigma-Aldrich L6010 α-Lactalbumin from bovine milk
description -	description Marker for non-denaturing PAGE	description Type I, ≥85% (PAGE), lyophilized powder	description Type III, calcium depleted, ≥85% (PAGE), lyophilized powder
technique(s) cell culture \| insect: suitable	technique(s) microbiological culture: suitable	technique(s) cell culture \| mammalian: suitable, electrophoresis: suitable	technique(s) indirect ELISA: suitable
biological source bovine	biological source bovine milk	biological source bovine milk	biological source bovine milk
Quality Level 200	Quality Level 200	Quality Level 300	Quality Level 300
form powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
Gene Information bovine ... LALBA(281894)	Gene Information cow ... LALBA(281894)	Gene Information cow ... LALBA(281894)	Gene Information cow ... LALBA(281894)
storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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