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D8008

7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

≥95%

Synonym(s):

DEDA

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About This Item

Empirical Formula (Hill Notation):
C22H40O2
CAS Number:
89560-01-0
Molecular Weight:
336.55
UNSPSC Code:
12352202
PubChem Substance ID:
24278388
MDL number:
MFCD00133010
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biological source

synthetic (organic)

assay

≥95%

form

liquid

storage temp.

−20°C

SMILES string

CCCCCCCCCCC\C=C/C(C)(C)\C=C/CCCC(O)=O

InChI

1S/C22H40O2/c1-4-5-6-7-8-9-10-11-12-13-16-19-22(2,3)20-17-14-15-18-21(23)24/h16-17,19-20H,4-15,18H2,1-3H3,(H,23,24)/b19-16-,20-17-

InChI key

AGKRHAILCPYNFH-DUQSFWPASA-N

Gene Information

human ... ADORA2A(135), ADORA2B(136)

Biochem/physiol Actions

Inhibitor of phospholipase A2 and lipoxygenase. Inhibits endogenous synthesis of leukotrienes.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKBS1160V
SLBB6164
110M1962
020M1379
019K1723

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Thomas L Williams et al.
Langmuir : the ACS journal of surfaces and colloids, 22(15), 6473-6476 (2006-07-13)
This letter describes a new method for studying the interaction of the membrane-lysing enzyme phospholipase A(2) (PLA(2)) with phospholipid bilayers by simultaneous measurements of enzyme binding and vesicle lysis using surface plasmon resonance (SPR) and permeabilization using surface plasmon field-enhanced
S Giri et al.
Journal of lipid research, 47(7), 1478-1492 (2006-04-29)
Globoid cell leukodystrophy (Krabbe disease) is an inherited neurological disorder caused by the pathogenomic accumulation of psychosine (galactosylsphingosine), a substrate for the deficient enzyme galactocerebroside beta-galactosidase. This study underscores the mechanism of action of psychosine in the regulation of oligodendrocyte
Jannike M Andersen et al.
Neurochemical research, 28(2), 319-326 (2003-03-01)
In this paper we show that exposure of a rat brain synaptosome fraction to the amyloid beta peptide fragment betaA(25-35), but not the inverted peptide betaA(35-25), stimulated production of reactive oxygen species (ROS) in a concentration- and time-dependent manner. The
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