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1,9-Dideoxyforskolin from Coleus forskohlii

Name: 1,9-Dideoxyforskolin from <I>Coleus forskohlii</I>
Brand: SIGMA

≥97%, solid

Synonym(s):

7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₄O₅

CAS Number:

64657-18-7

Molecular Weight:

378.50

NACRES:

NA.77

PubChem Substance ID:

24893774

UNSPSC Code:

41106305

MDL number:

MFCD00082318

Assay:

≥97%

Form:

solid

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Properties

Quality Segment

200

assay

≥97%

form

solid

optical activity

[α]26/D +93.6°, c = 6.12 in chloroform(lit.)

color

white to off-white

solubility

methanol: 28 mg/mL(lit.), DMSO: 3 mg/mL(lit.), chloroform: 50 mg/mL, ethanol: 6.6 mg/mL(lit.), dilute aqueous acid and base: insoluble(lit.)

storage temp.

−20°C

SMILES string

[H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)C3[C@@]1(C)CCCC2(C)C)C=C

InChI

1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16?,17-,18-,20-,21+,22-/m0/s1

InChI key

ZKZMDXUDDJYAIB-OJPJTMFRSA-N

Description

Application

Useful as a negative control for forskolin.

Biochem/physiol Actions

Biologically inactive forskolin analog. Does not stimulate adenylyl cyclase.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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1 of 1

This Item	344270	344282	1283255
Sigma-Aldrich D3658 1,9-Dideoxyforskolin from Coleus forskohlii	Sigma-Aldrich 344270 Forskolin, Coleus forskohlii	Sigma-Aldrich 344282 Forskolin, Coleus forskohlii in DMSO	USP 1283255 Powdered Forskohlii Extract
description ≥97%, solid	description -	description The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii.	description United States Pharmacopeia (USP) Reference Standard
assay ≥97%	assay ≥99% (HPLC)	assay ≥97% (HPLC)	assay -
form solid	form crystalline solid	form liquid	form -
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level -
storage temp. −20°C	storage temp. 10-30°C	storage temp. −20°C	storage temp. 15-25°C
solubility DMSO: 3 mg/mL(lit.), dilute aqueous acid and base: insoluble(lit.), methanol: 28 mg/mL(lit.), chloroform: 50 mg/mL, ethanol: 6.6 mg/mL(lit.)	solubility DMSO: 5 mg/mL	solubility -	solubility -
color white to off-white	color white to off-white	color -	color -

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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