D0754

3,5-Diiodo-L-tyrosine dihydrate

≥98.0% (HPLC), suitable for ligand binding assays

• Synonym(s): 3,5-diiodo-L-tyrosine hydrate (1:2)
• Empirical Formula (Hill Notation): C₉H₉I₂NO₃ · 2H₂O
• CAS Number: 18835-59-1
• Molecular Weight: 469.01
• NACRES: NA.26
• PubChem Substance ID: 24893289
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• EC Number: 206-092-0
• MDL number: MFCD00016542
• Beilstein/REAXYS Number: 2218691

Properties

• Product Name: 3,5-Diiodo-L-tyrosine dihydrate, crystalline
• assay: ≥98.0% (HPLC)
• Quality Segment: 200
• form: crystalline
• technique(s): ligand binding assay: suitable
• color: white
• mp: 200 °C (dec.) (lit.)
• solubility: 4 M NH₄OH in methanol: 50 mg/mL, clear, yellow-green
• storage temp.: −20°C
• SMILES string: N[C@@H](Cc1cc(I)c(O)c(I)c1)C(O)=O
• InChI: 1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1
• InChI key: NYPYHUZRZVSYKL-ZETCQYMHSA-N

Description

Application

Substrate for the assay of halogenated tyrosine and thyroid hormone aminotransferase. Intermediate in the biosynthesis and alternative pathways of metabolism of thyroid hormones.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves