52471

Fluorescein isothiocyanate–dextran

average mol wt 2,000,000

• Synonym(s): FITC–Dextran 2000, FITC–Dextran
• CAS Number: 60842-46-8
• UNSPSC Code: 12352201
• NACRES: NA.32
• MDL number: MFCD00131092

Properties

• biological source: synthetic
• Quality Segment: 100
• conjugate: FITC conjugate
• form: powder or crystals
• mol wt: average mol wt 2,000,000
• extent of labeling: 0.001-0.020 mol FITC per mol glucose (substitution)
• fluorescence: λ_ex 493 nm; λ_em 520 nm in 0.1 M Tris pH 8.0
• application(s): cell analysis

Description

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Fluorescein isothiocyanate–dextran (FITC–Dextran 2000) is use as a fluorescent probe to study the permeability of structures such as intercellular junctions involved in processes such as hearing and vascular permeability and the integrity of the blood brain barrier (BBB).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable