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Merck

8.52001

Fmoc-Gly-OH

Novabiochem®

Synonym(s):

Fmoc-Gly-OH, FMOC-Glycine, N-α-Fmoc-glycine

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About This Item

Empirical Formula (Hill Notation):
C17H15NO4
CAS Number:
Molecular Weight:
297.31
UNSPSC Code:
12352209
EC Index Number:
249-373-3
NACRES:
NA.22
MDL number:
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Quality Level

product line

Novabiochem®

assay

≥98% (TLC), ≥98.0% (acidimetric), ≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

177.4 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-30°C

SMILES string

N(CC(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)

InChI key

NDKDFTQNXLHCGO-UHFFFAOYSA-N

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General description

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of glycine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to off white
Appearance of substance (visual): powder
Color index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Gly-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Gly-Gly-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1001

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Yun Song et al.
Cell reports, 30(8), 2699-2711 (2020-02-27)
The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the

Global Trade Item Number

SKUGTIN
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852001025004027269206895
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852001902504027269242435
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852001901004027269221379

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