343333

5-Fluoro-2′-deoxyuridine

≥98% (HPLC), solid, thymidylate synthase inhibitor, Calbiochem^®

• Synonym(s): 5-Fluoro-2′-deoxyuridine, FdUrd, FUdR, 5-FdU, Floxuridine
• Empirical Formula (Hill Notation): C₉H₁₁FN₂O₅
• CAS Number: 50-91-9
• Molecular Weight: 246.19
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00006530
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: OK to freeze

Properties

• Product Name: 5-Fluoro-2′-deoxyuridine, Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.
• Quality Segment: 100
• description: Merck USA index - 14, 4112
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: aqueous buffer: 1 mg/mL, water: 1 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: Fc1[c]([nH][c]([n](c1)[C@@H]2O[C@@H]([C@H](C2)O)CO)=O)=O
• InChI: 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
• InChI key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N

Description

General description

Experimental anti-cancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Experimental anticancer agent

Product does not compete with ATP.

Reversible: no

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Nakagama, H., et al. 2001. Jpn. J. Clin. Oncol.31, 251.
Malmberg, M., et al. 1993. Cell Prolif. 26, 291.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H301
• Precautionary Statements: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3