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D-081

Supelco

Dopamine hydrochloride solution

1.0 mg/mL in methanol with 5% 1 M HCl (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C8H11NO2·HCl
CAS Number:
62-31-7
Molecular Weight:
189.64
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol with 5% 1 M HCl (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−70°C

SMILES string

Cl.NCCc1ccc(O)c(O)c1

InChI

1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

InChI key

CTENFNNZBMHDDG-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153)

General description

Dopamine is a catecholamine which acts as a neurotransmitter for dopamine receptors and neurohormone for regulation of numerous brain functions. This certified solution and linearity standard is suitable for LC/MS applications in diagnostic testing, endocrinology, and clinical chemistry.

Application

<ul>
<li><strong>Mass Spectrometry Metabolites in Inborn Errors of Metabolism Research:</strong> In research on very long-chain acyl-CoA dehydrogenase deficiency, Acylcarnitines IS Mix 2 is instrumental in metabolic profiling, helping to uncover metabolic alterations that are crucial for diagnosing and understanding inborn errors of metabolism (Bleeker et al., 2020).</li>
<li><strong>Fatty Acid Oxidation Studies:</strong> The mix is critical in research exploring the </ul>

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Takeshi Inoue et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 5927-5937 (2014-04-25)
LMTK3 belongs to the LMTK family of protein kinases that are predominantly expressed in the brain. Physiological functions of LMTK3 and other members of the LMTK family in the CNS remain unknown. In this study, we performed a battery of
Colter Mitchell et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5944-5949 (2014-04-09)
Disadvantaged social environments are associated with adverse health outcomes. This has been attributed, in part, to chronic stress. Telomere length (TL) has been used as a biomarker of chronic stress: TL is shorter in adults in a variety of contexts
Teruko Danjo et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), 6455-6460 (2014-04-17)
Dopamine (DA) transmission from the ventral tegmental area (VTA) is critical for controlling both rewarding and aversive behaviors. The transient silencing of DA neurons is one of the responses to aversive stimuli, but its consequences and neural mechanisms regarding aversive
A Jon Stoessl et al.
Lancet (London, England), 384(9942), 532-544 (2014-06-24)
Recent advances in structural and functional imaging have greatly improved our ability to assess normal functions of the basal ganglia, diagnose parkinsonian syndromes, understand the pathophysiology of parkinsonism and other movement disorders, and detect and monitor disease progression. Radionuclide imaging
Hanneke E M den Ouden et al.
Neuron, 80(4), 1090-1100 (2013-11-26)
Serotonin and dopamine are speculated to subserve motivationally opponent functions, but this hypothesis has not been directly tested. We studied the role of these neurotransmitters in probabilistic reversal learning in nearly 700 individuals as a function of two polymorphisms in
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