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A201

Sigma-Aldrich

Acenaphthenequinone

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About This Item

Empirical Formula (Hill Notation):
C12H6O2
CAS Number:
82-86-0
Molecular Weight:
182.17
Beilstein:
879172
EC Number:
201-441-3
MDL number:
MFCD00003805
UNSPSC Code:
12352200
PubChem Substance ID:
24890613
NACRES:
NA.77

form

powder

mp

249-252 °C (dec.) (lit.)

SMILES string

O=C1C(=O)c2cccc3cccc1c23

InChI

1S/C12H6O2/c13-11-8-5-1-3-7-4-2-6-9(10(7)8)12(11)14/h1-6H

InChI key

AFPRJLBZLPBTPZ-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M S C Henriques et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 172, 189-198 (2016-03-06)
The synthesis of a new hydrazone, 2-oxoacenaphthylen-1(2H)-ylidene nicotinohydrazide, and its structural and spectroscopic characterization is reported. The obtained powder was recrystallized from DMSO and ethanol that afforded small crystals used for single-crystal X-ray diffraction studies. The compound was found to
Sang Woon Chung et al.
Toxicological sciences : an official journal of the Society of Toxicology, 101(1), 152-158 (2007-10-11)
Quinoid polycyclic aromatic hydrocarbons are potent redox-active compounds that undergo enzymatic and nonenzymatic redox cycling with their semiquinone radical. We previously reported that acenaphthenequinone (AcQ) can damage human lung epithelial A549 cells through the formation of reactive species (RS). However
Kai Sheng et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 52(2), 127-134 (2016-10-22)
Quinones that exist in ambient particulate matter (PM) are hypothesized to be associated with adverse health effects through the generation of reactive oxygen species (ROS). However, the impacts of the quinones on the inflammatory processes have yet to be clearly
Tajia L Green et al.
Shock (Augusta, Ga.), 52(6), 590-597 (2019-01-25)
Glucocorticoids are widely used in the treatment of numerous inflammatory conditions, including sepsis. Unfortunately, patient response to glucocorticoid therapy can be inconsistent. Variations in the human glucocorticoid receptor (hGR) may contribute to the differential patient response. We screened for hGR
J M Varga et al.
Molecular immunology, 28(6), 655-659 (1991-06-01)
Serotonin release from rat basophilic leukemia (RBL) cells, sensitized with a DNP-binding monoclonal IgE, was stimulated with solid surface (polystyrene)-bound DNP-amino acids. The stimulatory potency of DNP-amino acids was dependent on the structure of amino acid attached to DNP. Generally
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