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900671

Sigma-Aldrich

Methoxy poly(ethylene glycol)-block-poly(ε-caprolactone)

5k-2k

Synonym(s):

mPEG-b-PCL, mPEG-PCL

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About This Item

Linear Formula:
CH3O(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

form

powder

mol wt

PCL average Mn ~2,000
PEG average Mn ~5,000

transition temp

flash point >230 °F
Tm 54-57 °C

storage temp.

2-8°C

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Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Simple solvothermalsynthesis of hydrophobic magnetic monodispersed Fe3O4 nanoparticles.
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Metastatic melanoma has a high mortality rate due to lymphatic progression of the disease. Current treatment is surgery followed by radiation and intravenous chemotherapy. However, drawbacks for current chemotherapeutics lie in the fact that they develop resistance and do not

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