256536

Phosphorus tribromide

99%

• Synonym(s): Phosphorus(III) bromide
• Linear Formula: PBr₃
• CAS Number: 7789-60-8
• Molecular Weight: 270.69
• EC Number: 232-178-2
• MDL number: MFCD00011436
• UNSPSC Code: 12352101
• PubChem Substance ID: 24855534
• NACRES: NA.22

Properties

• vapor pressure: 0.27 psi ( 54 °C)
• Assay: 99%
• form: liquid
• refractive index: n20/D 1.697 (lit.)
• bp: 175 °C (lit.)
• mp: −41.5 °C (lit.)
• density: 2.88 g/mL at 20 °C (lit.)
• SMILES string: BrP(Br)Br
• InChI: 1S/Br3P/c1-4(2)3
• InChI key: IPNPIHIZVLFAFP-UHFFFAOYSA-N

Description

General description

Phosphorus tribromide (PBr₃) is commonly used in Hell-Volhard-Zelinsky halogenation for the α-bromination of carboxylic acids to form the corresponding acyl bromide. It is also useful for the conversion of primary and secondary alcohols to alkyl bromides.

Application

Phosphorus tribromide may be used as a reagent:

• In a novel protocol for synthesizing 7-ethoxy-1-(p-ethylphenoxy)-3,7-dimethyl-2-octene, a synthetic juvenile hormone mimic of trans,trans,cis-10,11-epoxy-7-ethyl-3,11-dimethyltrideca-2,6-dienoate.
• To synthesize 1,2,3-diazaphosphinane, 1,2,3-thiazaphosphinine and 1,2-azaphosphole bearing a chromone ring.
• To synthesize 1-Bromoundec-1-ene from 10-undecen-1-ol.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H314,H335
• Precautionary Statements: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves