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Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides.

Bioorganic & medicinal chemistry letters (2009-12-08)
Abdelselam Ali, Petr Fisara, Jamie A Freemont, Stella Kyi, Adam G Meyer, Andrew G Riches, Roger M Sargent, David G Sawutz, Kathleen A Turner, Kevin N Winzenberg, Qi Yang
RÉSUMÉ

A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.

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1-Aminohydantoin hydrochloride, 98%