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Principaux documents

53255-U

Supelco

supelMIP® SPE - NNAL

96-well plate, bed wt. 25 mg/well, pk of 1

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About This Item

Code UNSPSC :
41115712
Nomenclature NACRES :
NB.21

Matériaux

polypropylene tube

Gamme de produits

SupelMIP®
SupelMIP®

Composition

bed wt., 25 mg/well

Conditionnement

pk of 1

Technique(s)

solid phase extraction (SPE): suitable

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Description générale

SupelMIP SPE phases were developed by MIP Technologies AB, which is one of the leading authorities and commercial pioneers of molecular imprinted polymers for process scale separations, analytical chromatography, and sample preparation.

The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.

By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.

Visit www.sigma-aldrich.com/supelmip to learn more.

Application

A highly selective MIP phase for the selective extraction of tobacco-specific nitrosamine NNAL in biological fluids.

Unlike conventional extraction methods which are elaborate and time-consuming, SupelMIP SPE - NNAL offers a simple and efficient extraction method for quantitating NNAL (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol). The method offers consistent and excellent selectivity and recoveries for both free and total NNAL with and without the presence of nicotine. Detailed extraction protocols are included with the product.

Caractéristiques et avantages

  • Highly selective SPE for trace analysis in complex matrices
  • Achieve lower detection limits
  • Significant time and cost savings
  • Improved MS-compatibility

Informations légales

SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
14165801
13497001
13478701
13480401
12983601

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Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

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Contenu apparenté

SupelMIP Molecularly Imprinted Polymer SPE Cartridges

SupelMIP SPE is based on molecularly imprinted polymer (MIP) technology. Each SupelMIP phase offers tailor-made selectivity for the extraction of trace analytes in complex matrixes.

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