SRP6206

sCD22 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Synonyme(s) : B Lymphocyte cell adhesion molecule, BL-CAM, Leu-14, Siglec-2
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Produit recombinant: expressed in E. coli
• Essai: ≥98% (SDS-PAGE)
• Forme: lyophilized powder
• Poids mol.: ~75 kDa
• Conditionnement: pkg of 10 μg; pkg of 50 μg
• Impuretés: <1 EU/μg endotoxin (LAL test)
• Numéro d'accès UniProt: P20273
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: human ... CD22(933)

Description

Description générale

CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.

Forme physique

Sterile filtered through a 0.2 micron filter. Lyophilized from 1X PBS, pH 7.2.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable