SRP4187
IL-27 from mouse
recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
Synonyme(s) :
IL 27, Interleukin27
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About This Item
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.32
Source biologique
mouse
Produit recombinant
expressed in E. coli
Essai
≥97% (HPLC)
≥97% (SDS-PAGE)
Forme
lyophilized
Poids mol.
~23.7 kDa
Conditionnement
pkg of 10 μg
Impuretés
endotoxin, tested
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Informations sur le gène
mouse ... Il27(246779)
Description générale
Recombinant mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of Cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23.7 kDa.
Forme physique
Lyophilized from 10 mM NaP, pH 7.5.
Reconstitution
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.
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Denada Dibra et al.
PloS one, 6(4), e19072-e19072 (2011-05-12)
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Jui-Hung Yen et al.
Journal of leukocyte biology, 98(5), 689-702 (2015-06-11)
MS is an autoimmune disease characterized by immune cell infiltration in the CNS, leading to cumulative disability. IFN-β, used clinically in RR-MS reduces lesion formation and rates of relapse. Although the molecular mechanisms are not entirely elucidated, myeloid cells appear
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