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Unfortunately, we do not determine the conformation of this product.
SML0982
Astaxanthin
from Blakeslea trispora, ≥97% (HPLC), powder, PPARγ
Synonyme(s) :
3,3′-Dihydroxy-β-carotene-4,4′-dione, trans-Astaxanthin
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50 MG
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161,00 $
About This Item
Formule empirique (notation de Hill) :
C40H52O4
Numéro CAS:
Poids moléculaire :
596.84
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.77
Produits recommandés
Nom du produit
Astaxanthin, ≥97% (HPLC), from Blakeslea trispora
Source biologique
Blakeslea trispora
Essai
≥97% (HPLC)
Forme
powder
Conditions de stockage
desiccated
protect from light
Couleur
, pink to very dark purple
Solubilité
DMSO: 1 mg/mL (warmed)
Température de stockage
−20°C
Chaîne SMILES
O[C@H]1CC(C(=C(C1=O)C)\C=C\C(=C\C=C\C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)(C)C
InChI
1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
Clé InChI
MQZIGYBFDRPAKN-UWFIBFSHSA-N
Description générale
Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis.[1]
Application
Astaxanthin has been used:
- as an antioxidant to study its effect on Brachionus manjavacas (Rotifera) population growth[2]
- to study its effects on the treatment of diabetic retinopathy.[2][3]
- to investigate its role in restoring the expression of Nrf2 (nuclear factor erythroid 2 p45-related factor 2) and glutathione S-transferase P1 (GSTP1) through epigenetic modification in human prostate LNCaP cells.[1]
Actions biochimiques/physiologiques
In vivo and in vitro studies propose that astaxanthin (AST) possesses health-promoting activities, signifying its potential use in the prevention of various diseases, such as cancers and Parkinson′s disease.[1] Due to its bright red colour, AST has been used as a food colorant in animal feeds.[3]
Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.
Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory compounds nitric oxide, prostaglandin E2, TNF-α, and interleukin-1β. Astaxanthin′s protection of cells from oxidative stress generated by TNF-α and palmitate has been shown to ameliorate insulin resistance. Astaxanthin has also been shown to be an inhibitor of PPARγ.
Autres remarques
Light and air sensitive
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Les clients ont également consulté
Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth.
Johnston R K, et al.
Aquaculture Research, 49(6), 2278-2287 (2018)
Shreya Agrawal et al.
Plant physiology (2021-10-09)
The high-value carotenoid astaxanthin (3,3'-dihydroxy-β,β-carotene-4,4'-dione) is one of the most potent antioxidants in nature. In addition to its large-scale use in fish farming, the pigment has applications as a food supplement and an active ingredient in cosmetics and in pharmaceuticals
Ningyang Li et al.
Applied microbiology and biotechnology, 104(16), 6977-6989 (2020-07-01)
This study aimed to develop a bioprocess using plant oil as the carbon source for lipid-assimilating yeast to produce high-value astaxanthin. Using high-oleic safflower oil as a model, efficient cell growth and astaxanthin production by the engineered Yarrowia lipolytica strain
Yingsong Zhou et al.
Nutrients, 11(6) (2019-06-05)
Exercise-induced reactive oxygen and nitrogen species are increasingly considered as beneficial health promotion. Astaxanthin (ASX) has been recognized as a potent antioxidant suitable for human ingestion. We investigated whether ASX administration suppressed antioxidant enzyme activity in moderate-intensity exercise. Seven-week-old male
Jada Bittle et al.
Cerebral cortex (New York, N.Y. : 1991), 29(12), 5116-5130 (2019-03-17)
Maternal stress during pregnancy is associated with increased risk of psychiatric disorders in offspring, but embryonic brain mechanisms disrupted by prenatal stress are not fully understood. Our lab has shown that prenatal stress delays inhibitory neural progenitor migration. Here, we
Articles
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
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Is the Astaxanthin SML0982 in the 3S, 3'S conformation or is it a mix?
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