SAB5701903

Anti-Phospho-PKR/EIF2AK2-T446 antibody produced in rabbit

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: monoclonal
• Forme: liquid
• Espèces réactives: human, mouse, rat
• Concentration: 0.84 mg/mL
• Technique(s): western blot: 1:500-1:2000
• Numéro d'accès UniProt: P19525
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pThr446)
• Informations sur le gène: human ... EIF2AK2(5610)

Description

Description générale

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Immunogène

A phospho specific peptide corresponding to residues surrounding T446 of human PKR/EIF2AK2

Forme physique

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable