SAB5700707

Anti-HIF1A antibody produced in rabbit

• Synonyme(s) : HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1A, MOP1, PASD8, bHLHe78
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.43

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 82; 92; 95
• Espèces réactives: mouse, human, rat
• Concentration: 1.29 mg/ml
• Technique(s): western blot: 1:500-1:2000
• Numéro d'accès UniProt: Q16665
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... HIF1A(3091)

Description

Description générale

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Immunogène

Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of human HIF1A (NP_851397.1).

Forme physique

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Stockage et stabilité

Store at -20℃. Avoid freeze / thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable