SAB5202071

Monoclonal Anti-beta 4 Spectrin-Horseradish Peroxidase antibody produced in mouse

clone S393-2, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-SPTBN4
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.45

Propriétés

• Source biologique: mouse
• Conjugué: peroxidase conjugate
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: S393-2; monoclonal
• Description: clone S393-2, purified immunoglobulin, buffered aqueous solution; target molecular weight: 200 kDa
• Forme: buffered aqueous solution
• Espèces réactives: human (Tested), rat (Predicted), African green monkey (Tested), mouse (Predicted)
• Conditionnement: pkg of 100 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles; protect from light
• Concentration: 1.0 mg/mL
• Technique(s): immunofluorescence: 1:100; western blot: 1:1000
• Isotype: IgG1
• Numéro d'accès UniProt: Q9H254
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... SPTBN4(57731)

Description

Immunogène

Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin

Immunogen Region: C-terminal

Immunogen Species: Human

Immunogen type: Fusion protein

Application

Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His

Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE

Forme physique

50% glycerol, 0.1% sodium azide

PBS pH 7.4

Notes préparatoires

Derived from animal serum

Stockage et stabilité

Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.

Autres remarques

Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase

Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable