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SAB5200105

Sigma-Aldrich

Anti-SCNN1A antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Synonyme(s) :

Anti-ENaC Alpha, Anti-Scnn1a

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous glycerol solution

Poids mol.

antigen predicted mol wt 85 kDa

Espèces réactives

rat, mouse

Concentration

1 mg/mL

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès UniProt

Q61180

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

rat ... Scnn1a(25122)

Description générale

Sodium channel epithelial 1 α subunit (SCNN1A) is one of the subunits of epithelial sodium channels. The gene ID of the protein is 25122.

Spécificité

Detects ~85 kDa.

Immunogène

AA46–68 of the rat sequence

Actions biochimiques/physiologiques

Sodium channel epithelial 1 α subunit (SCNN1A) deals with sodium transport in the lungs and kidneys of rats.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

PBS, 50% glycerol, and 0.09% sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Megan M Greenlee et al.
American journal of physiology. Lung cellular and molecular physiology, 305(11), L878-L889 (2013-10-08)
Female sex predisposes individuals to poorer outcomes during respiratory disorders like cystic fibrosis and influenza-associated pneumonia. A common link between these disorders is dysregulation of alveolar fluid clearance via disruption of epithelial sodium channel (ENaC) activity. Recent evidence suggests that
Md Shahrier Amin et al.
Hypertension (Dallas, Tex. : 1979), 54(4), 860-867 (2009-07-29)
To elucidate the role of epithelial sodium channels (ENaCs) and Na(+)-K(+)-ATPase in Na(+) transport by the choroid plexus, we studied ENaC expression and Na(+) transport in the choroid plexus. Lateral ventricle choroid plexuses were obtained from young male Wistar, Dahl
Xin-Peng Duan et al.
Hypertension (Dallas, Tex. : 1979), 73(1), 112-120 (2018-12-21)
The stimulation of β-adrenergic receptor increases thiazide-sensitive NaCl cotransporter (NCC), an effect contributing to salt-sensitive hypertension by sympathetic stimulation. We now test whether the stimulation of β-adrenergic receptor-induced activation of NCC is achieved through activating basolateral Kir4.1 in the distal
Adverse effect of assisted reproductive technology-related hyperoestrogensim on the secretion and absorption of uterine fluid in superovulating mice during the peri-implantation period.
Xia, et al.
Frontiers in Endocrinology, 14, 859204-859204 (2023)

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