SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• Synonyme(s) : NGFR, TNFRSF16, p75NGFR, p75NTR
• Code UNSPSC : 12352203

Propriétés

• Conjugué: unconjugated
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: NGFR5, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: human, ( Non-human primates), ( Rabbit), ( Cat)
• Concentration: 1 mg/ml
• Technique(s): flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotype: IgG1
• Numéro d'accès UniProt: P08138
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... NGFR(4804)

Description

Description générale

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Spécificité

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Immunogène

Purified CD271 protein isolated from human melanoma cell line A875

Forme physique

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Notes préparatoires

Purified by protein-A affinity chromatography.

Stockage et stabilité

Store at 2-8°C. Do not freeze.

Autres remarques

The antibody solution should be gently mixed before use.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable