SAB4502896

Anti-CD147, C-Terminal antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : BASI, CD147, basigin, basigin (Ok blood group), collagenase stimulatory factor
• Numéro MDL: MFCD02262857
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 42 kDa
• Espèces réactives: mouse, human, rat
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P35613
• Numéro d'accès UniProt: P35613
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... BSG(682)

Description

Description générale

Anti-CD147 Antibody detects endogenous levels of total CD147 protein.
Cluster of differentiation 147 (CD147) is a multifunctional trans-membrane glycoprotein and is a member of the immunoglobulin superfamily. It occurs in transmembrane and soluble forms. CD147 is also known as EMMPRIN or basigin (BSG). It is a 57 kDa glycoprotein with two extracellular Ig domains. CD147 is located on human chromosome 19p13.

Immunogène

The antiserum was produced against synthesized peptide derived from human CD147.

Immunogen Range: 336-385

Application

Anti-CD147, C-Terminal antibody has been used in western blotting.

Actions biochimiques/physiologiques

Cluster of differentiation 147 (CD147) is considered as an extracellular matrix metalloproteinase inducer. It participates in several physiological and pathological activities, mainly in tumor invasion and metastasis. CD147 helps in tumor cell-macrophage interactions and stimulates MMPs (matrix metalloproteinases) and vascular endothelial growth factor (VEGF).

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable