SAB4300685

Anti-ASH2L antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-ASH2, Anti-ASH2L1, Anti-ASH2L2, Anti-Bre2
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 65-80 kDa
• Espèces réactives: human
• Concentration: 1 mg/mL
• Technique(s): western blot: 1:500-1:1000
• Isotype: IgG
• Séquence immunogène: (G-R-R-S-P)
• Numéro d'accès NCBI: NM_004674.3
• Numéro d'accès UniProt: Q9UBL3
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ASH2L(9070)

Description

Description générale

The antibody detects endogenous level of total ASH2L protein.

Immunogène

Peptide sequence around aa. 620-624 (G-R-R-S-P), according to the protein NP_004665.2

Caractéristiques et avantages

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Description de la cible

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates ′Lys-4′ of histone H3, but not if the neighboring ′Lys-9′ residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ′Lys-4′ of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable