SAB4100383

Monoclonal Anti-TMOD1 antibody produced in mouse

clone TMOD1-A328, culture supernatant

• Synonyme(s) : Anti-D9S57E, Anti-ETMOD, Anti-TMOD, Anti-tropomodulin 1
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: TMOD1-A328, monoclonal
• Forme: aqueous solution
• Poids mol.: antigen predicted mol wt 40.4 kDa
• Espèces réactives: human
• Technique(s): western blot: suitable
• Isotype: IgG2b
• Numéro d'accès UniProt: P28289
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Informations sur le gène: human ... TMOD1(7111)

Description

Description générale

Tropomodulin 1 (TMOD1) is an actin-capping protein, which is expressed in the cardiac muscle and in slow-twitch muscle fibers. It possesses two actin- and two tropomyosin (TM)-binding regions. The gene encoding this protein is localized on human chromosome 9q.[1][2][3]

Immunogène

TMOD1 purified recombinant protein

Actions biochimiques/physiologiques

Tropomodulin 1 (TMOD1) prevents the elongation and depolymerization of actin filaments by binding to the slowly growing pointed end of the actin filament. It has been associated with triple-negative breast cancers (TNBC). TMOD1 may act as a stabilizer of β-catenin.[4][1]

Forme physique

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable