SAB3500390
Anti-ELOVL7 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonyme(s) :
Anti-Elongation of very long chain fatty acids protein 7
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100 μG
720,00 $
720,00 $
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100 μG
720,00 $
About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
720,00 $
Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
buffered aqueous solution
Espèces réactives
human, mouse
Technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... ELOVL7(79993)
Catégories apparentées
Description générale
ELOVL (Elongation of very long chain fatty acids) fatty acid elongase 7 is expressed in most tissues except heart and skeletal muscles. In human chromosome, the gene ELOVL7 is localised on 5q12.1.
Immunogène
ELOVL7 antibody was raised against a 15 amino acid peptide near the amino terminus of human ELOVL7.
Actions biochimiques/physiologiques
ELOVL7 catalyses the elongation of long chain fatty acids, preferably saturated long chain fatty acids. Elovl7 exhibited activity towards C16-C20 acyl coenzyme A with maximum affinity towards carbon length of C18. Elovl7 expression is regulated by sterol regulatory element-binding protein 1 (SREBP1) and also by other lipogenic enzymes. The expression levels of Elovl7 is higher in prostate cancer leading to its progression.
Caractéristiques et avantages
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Liaison
The action of this antibody can be blocked using blocking peptide SBP3500390.
Forme physique
Supplied in PBS with 0.02% sodium azide.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Cockayne syndrome caused by paternally inherited 5Mb deletion of 10q11. 2 and a frameshift mutation of ERCC6
Ghai SJ, et al.
European Journal of Medical Genetics, 54(3), 272-276 (2011)
Yuecheng Xi et al.
Journal of virology, 93(21) (2019-08-09)
Human cytomegalovirus (HCMV) replication requires host metabolism. Infection alters the activity in multiple metabolic pathways, including increasing fatty acid elongation and lipid synthesis. The virus-host interactions regulating the metabolic changes associated with replication are essential for infection. While multiple host
Kenji Tamura et al.
Cancer research, 69(20), 8133-8140 (2009-10-15)
A number of epidemiologic studies have indicated a strong association between dietary fat intake and prostate cancer development, suggesting that lipid metabolism plays some important roles in prostate carcinogenesis and its progression. In this study, through our genome-wide gene expression
Yusuke Ohno et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(43), 18439-18444 (2010-10-13)
Very long-chain fatty acids (VLCFAs) exert a variety of cellular functions and are associated with numerous diseases. However, the precise pathway behind their elongation has remained elusive. Moreover, few regulatory mechanisms for VLCFAs synthesis have been identified. Elongases catalyze the
Tatsuro Naganuma et al.
FEBS letters, 585(20), 3337-3341 (2011-10-01)
Very long-chain fatty acids (VLCFAs) have a variety of physiological functions and are related to numerous disorders. The key step of VLCFA elongation is catalyzed by members of the elongase family, ELOVLs. Mammals have seven ELOVLs (ELOVL1-7), yet none of
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