SAB3500033

Anti-ZBED3 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution, ab2

• Synonyme(s) : Anti-Zinc finger BED-type domain containing 3
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: predicted mol wt 26 kDa
• Espèces réactives: human, rat, mouse
• Technique(s): indirect ELISA: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_115743
• Numéro d'accès UniProt: Q96IU2
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ZBED3(84327)

Description

Immunogène

ZBED3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ZBED3.

Caractéristiques et avantages

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Description de la cible

Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

Liaison

The action of this antibody can be blocked using blocking peptide SBP3500033.

Forme physique

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable