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Key Documents

COO/COA

RAB1228

Feline CXCL1 ELISA

Name: Feline CXCL1 ELISA
Brand: SIGMA

for serum, plasma and cell culture supernatants

Synonyme(s) :

C-X-C motif chemokine 1, Growth-regulated alpha protein, Platelet-derived growth factor-inducible protein KC, Secretory protein N51

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About This Item

Code UNSPSC :

41116158

Nomenclature NACRES :

NA.32

Espèces réactives

feline

Technique(s)

ELISA: suitable

assay range

inter-assay cv: <12%
intra-assay cv: <10%

Conditions d'expédition

wet ice

Température de stockage

−20°C

Description générale

Chemokine (C-X-C motif) ligand 1 (CXCL1), a member of the CXC chemokine family, is a small cytokine expressed by epithelial cells, macrophages, and neutrophils. It can stimulate progression, tumorigenesis, and recurrence in bladder cancer, pancreatic cancer, and glioma. CXCL1 is capable of specifically binding to the G protein-coupled receptor chemokine (C-X-C motif) receptor 2 (CXCR2). This ELISA antibody pair detects feline chemokine (C-X-C motif) ligand 1 (CXCL1).

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Autres remarques

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictogrammes

GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Elevation of CXCL1 indicates poor prognosis and radioresistance by inducing mesenchymal transition in glioblastoma.

Wahafu Alafate et al.

CNS neuroscience & therapeutics, 26(4), 475-485 (2020-03-19)

Glioblastoma (GBM) is identified as a lethal malignant tumor derived from the nervous system. Despite the standard clinical strategy including maximum surgical resection, temozolomide (TMZ) chemotherapy, and radiotherapy, the median survival of GBM patients remains <15 months. Accumulating evidence indicates that

CXCL1 stimulates migration and invasion in ER‑negative breast cancer cells via activation of the ERK/MMP2/9 signaling axis.

Chengcheng Yang et al.

International journal of oncology, 55(3), 684-696 (2019-07-20)

Chemokine (C‑X‑C motif) ligand 1 (CXCL1), a member of the CXC chemokine family, has been reported to be a critical factor in inflammatory diseases and tumor progression; however, its functions and molecular mechanisms in estrogen receptor α (ER)‑negative breast cancer (BC) remain largely unknown. The

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