R4780

RACK1 human

recombinant, expressed in E. coli, >90% (SDS-PAGE), buffered aqueous solution

• Synonyme(s) : Receptor for activated protein kinase C
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Produit recombinant: expressed in E. coli
• Essai: >90% (SDS-PAGE)
• Forme: buffered aqueous solution
• Poids mol.: 37 kDa
• Numéro d'accès UniProt: P63244
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Informations sur le gène: human ... GNB2L1(10399)

Description

Actions biochimiques/physiologiques

RACK1 (receptor of activated protein kinase C1) is an intracellular adapter protein, which belongs to a class of intracellular receptor proteins that bind activated members of the protein kinase C family. RACK1 serves as a scaffold protein for a wide range of kinases and membrane-bound receptors. RACK1 is a member of the tryptophane-aspartate (WD) family known for its propeller-like structure. Literature strongly indicates that RACK1 plays an important role in intracellular signaling at several functional levels. RACK1, a substrate for several kinases, is involved in the regulation of Src function and cell growth.

RACK1 is an intracellular receptor protein that binds activated members of the protein kinase C family.

Forme physique

Supplied in a 0.2 μm filtered solution of 0.02 M Tris buffer, pH 8.0, with 0.15 M NaCl, 5 mM DTT, 0.1% CHAPS, and 30% glycerol (w/v).

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)