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MAK261

Sigma-Aldrich

Glycine Assay Kit (Fluorometric)

sufficient for 100 fluorometric tests

Synonyme(s) :

Fluorometric Glycine Detection Kit

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Méthode de détection

fluorometric

Maladie(s) pertinente(s)

cancer; neurological disorders

Température de stockage

−20°C

Description générale

Glycine (GLY) is a non-essential amino acid used to help create muscle tissue and convert glucose into energy. It′s basic functions include the participation in the synthesis of creatine, glutathione, heme groups, and conjugated bile acids (bile salts). It is also used in the synthesis of DNA and RNA. It is one of the most abundant residues in the triple-helical structure of collagen, which contributes to the elasticity of skin and connective tissue. It acts as a glucogenic amino acid regulating blood sugar levels. Glycine is necessary for central nervous system function. It possesses both inhibitory and excitatory neurotransmitter functions in the brain stem and spinal cord. Recent studies suggest, glycine may play a role in tumorigenesis and malignancy. Some of the external sources of glycine includes legumes, meat, fish and dairy products.[1]

Caractéristiques et avantages

Compatible with high-throughput handling systems.

Adéquation

Suitable for the detection of glycine in biological fluids such as serum, plasma, saliva, urine, etc

Principe

The Glycine Assay Kit is a simple and reliable, high throughput assay that detects the physiological concentration of glycine in a variety of biological fluids. In the assay, glycine is oxidized generating a fluorometric (lex = 535 nm/ lem = 587 nm) product, proportional to the glycine present. The assay is specific, and other standard and non-standard amino acids do not interfere with the assay. The kit is sensitive to 1 mM of glycine.

Pictogrammes

Health hazardCorrosion
GHS08,GHS05

Mention d'avertissement

Danger

Mentions de danger

H290,H317,H334

Classification des risques

Met. Corr. 1 - Resp. Sens. 1 - Skin Sens. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Consulter la Bibliothèque de documents

Tae Seok Oh et al.
JCI insight, 7(12) (2022-06-23)
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to an infection. The metabolic aberrations associated with sepsis underly an acute and organism-wide hyperinflammatory response and multiple organ dysfunction; however, crosstalk between systemic metabolomic alterations and metabolic reprogramming
Resnick A.
The Bone Broth Miracle: How an Ancient Remedy Can Improve Health, Fight Aging, and Boost Beauty (2015)
Joan Artigas et al.
Environmental pollution (Barking, Essex : 1987), 259, 113951-113951 (2020-01-16)
Environmental dissolved organic matter (DOM) has been proved to increase microbial population sizes and stimulate the degradation of some pesticide molecules. Among these molecules, the present study investigated the biodegradation of the herbicide glyphosate depending on photoautotrophs DOM supply in

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