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Principaux documents

M7031

Sigma-Aldrich

13-Methylmyristic acid

≥98% (capillary GC)

Synonyme(s) :

13-Methyltetradecanoic acid

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About This Item

Formule empirique (notation de Hill) :
C15H30O2
Numéro CAS:
Poids moléculaire :
242.40
Numéro MDL:
Code UNSPSC :
12352211
ID de substance PubChem :

Essai

≥98% (capillary GC)

Forme

solid

Groupe fonctionnel

carboxylic acid

Conditions d'expédition

ambient

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)CCCCCCCCCCCC(O)=O

InChI

1S/C15H30O2/c1-14(2)12-10-8-6-4-3-5-7-9-11-13-15(16)17/h14H,3-13H2,1-2H3,(H,16,17)

Clé InChI

ZOCYQVNGROEVLU-UHFFFAOYSA-N

Actions biochimiques/physiologiques

13-Methyltetradecanoic acid (13-Methylmyristic acid, 13-MTD, 13-MTDA), an iso-fatty acid, is used to study the induction of mitochondrial-mediated apoptosis via the AKT and MAPK pathways. 13-MTDA is used for the biosynthesis of methyl-branched polyhydroxyalkanoates.

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Consulter la Bibliothèque de documents

Sawitree Wongtangtintharn et al.
Lipids in health and disease, 4, 29-29 (2005-11-25)
13-Methyltetradecanoic acid (13-MTD), an iso-C15 branched- chain saturated fatty acid, has been shown to induce apoptotic cell death of numerous human cancer cells. However, the mechanism for the induction of apoptosis has not been fully understood. This study described the
N Kadri-Hassani et al.
The Journal of biological chemistry, 270(25), 15111-15118 (1995-06-23)
We studied the translocation of protein kinase C (PKC), the endogenous phosphorylation and presence in the membrane fraction of p47phox (the 47-kDa cytosolic component of the phagocyte NADPH oxidase), and the O-.2 production in human adherent monocytes (HAMs). This was
Z Yang et al.
Cancer research, 60(3), 505-509 (2000-02-17)
A saturated branched-chain fatty acid, 13-methyltetradecanoic acid (13-MTD), was purified from a soy fermentation product, which was used by many cancer patients as a treatment supplement. Our preliminary study indicated that 13-MTD could induce cell death in human cancer cell
Tianxin Lin et al.
Urologic oncology, 30(3), 339-345 (2010-09-17)
13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid purified from soy fermentation products, is known to induce apoptosis in many types of human cancer cells. This study was designed to investigate the molecular mechanisms involved in 13-MTD-induced apoptosis in human
Sawitree Wongtangtintharn et al.
Journal of nutritional science and vitaminology, 50(2), 137-143 (2004-07-10)
This paper describes the antitumoral activity of branched-chain fatty acid (BCFA) in human breast cancer cells with an emphasis on its effect on fatty acid biosynthesis. First, the relationship between chain-length and antitumoral activity was studied. The highest activity was

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