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D2178

Monoclonal Anti-Death Associated Protein Kinase antibody produced in mouse

Name: Monoclonal Anti-Death Associated Protein Kinase antibody produced in mouse
Brand: SIGMA
Price: 768 CAD

clone DAPK-55, ascites fluid

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Synonyme(s) :

Anti-DAP Kinase

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Taille/Référence	Disponibilité	Prix
0.2 mL	Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.	768,00 $

A propos de cet article

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00282220

Conjugate:

unconjugated

Clone:

DAPK-55, monoclonal

Application:

ARR, IP, WB

Citations:

768,00 $

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Propriétés

Quality Segment

200

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

DAPK-55, monoclonal

mol wt

antigen 160 kDa

contains

15 mM sodium azide

species reactivity

human, monkey

technique(s)

immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1:250 using COS-7 cell extract

isotype

IgG1

UniProt accession no.

P51397

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DAP(1611)

Description

General description

Monoclonal Anti-Death Associated Protein (DAP) Kinase (mouse IgG1 isotype) is derived from the DAPK-55 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. Death-associated protein 1 (DAP1) gene is mapped to human chromosome 9q34.1. It belongs to the DAP family.

The gene is widely expressed in many tissues of embryonic and adult origin and gives rise to a single 6.3 Kb mRNA transcript. The protein consists of 1423 amino acids (160 kDa) and belongs to a family of calmodulin-dependent protein kinases. It contains 8 ankyrin repeats and 2 potential P-loop motifs apart from the kinase domain and the calmodulin regulatory domain.

Immunogen

recombinant human DAP kinase expressed in bacteria.

Application

Monoclonal Anti-Death Associated Protein Kinase antibody produced in mouse has been used in immunoblotting and immunoprecipitation.

Biochem/physiol Actions

DAP-kinase is a novel, structurally unique, human serine/threonine kinase identified as a positive mediator of interferon-γ-induced programmed cell death. It has an intrinsic kinase activity towards itself that is regulated by calmodulin and calcium.

Death-associated protein 1 (DAP1) participates in the regulation of cell growth and death including that of cancer cells. DAP-kinase has an intrinsic kinase activity towards itself that is regulated by calmodulin and calcium.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Cet article	D1319	D4941	ABC259
Sigma-Aldrich D2178 Monoclonal Anti-Death Associated Protein Kinase antibody produced in mouse	Sigma-Aldrich D1319 Anti-DAP Kinase 1 antibody produced in rabbit	Sigma-Aldrich D4941 Anti-phospho-DAP-Kinase (pSer³⁰⁸) antibody, Mouse monoclonal	Sigma-Aldrich ABC259 Anti-Death-associated protein 1 Antibody
description clone DAPK-55, ascites fluid	description ~1 mg/mL, affinity isolated antibody, buffered aqueous solution	description clone DKPS308, purified from hybridoma cell culture	description 1.0 mg/mL, from rabbit
clone DAPK-55, monoclonal	clone polyclonal	clone DKPS308, monoclonal	clone polyclonal
species reactivity human, monkey	species reactivity mouse (predicted), human, rat (predicted)	species reactivity human	species reactivity human, mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form ascites fluid	antibody form affinity isolated antibody	antibody form purified from hybridoma cell culture	antibody form affinity isolated antibody
biological source mouse	biological source rabbit	biological source mouse	biological source rabbit
Gene Information human ... DAP(1611)	Gene Information human ... DAPK1(1612) mouse ... Dapk1(69635) rat ... Dapk1(306722)	Gene Information human ... DAPK1(1612)	Gene Information human ... DAP(1611)

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