B7652

Betamethasone 21-phosphate disodium

≥97%, glucocorticoid steroid, powder

• Synonyme(s) : Betamethasone disodium phosphate, Betamethasone sodium phosphate
• Formule empirique (notation de Hill) : C₂₂H₂₈FNa₂O₈P
• Numéro CAS: 151-73-5
• Poids moléculaire : 516.40
• NACRES: NA.77
• PubChem Substance ID: 24892013
• UNSPSC Code: 12352200
• EC Number: 205-797-0
• MDL number: MFCD00200361
• Assay: ≥97%
• Form: powder

Propriétés

• Nom du produit: Betamethasone 21-phosphate disodium, ≥97%
• sterility: non-sterile
• Quality Segment: 100
• assay: ≥97%
• form: powder
• solubility: water: 50 mg/mL, clear to very slightly hazy, faintly yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O
• InChI: 1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1
• InChI key: PLCQGRYPOISRTQ-LWCNAHDDSA-L
• Gene Information: human ... NR3C1(2908)

Description

General description

Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants

Biochem/physiol Actions

Betamethasone is used to treat neonatal respiratory distress syndrome, and psoriasis.

Informations sur la sécurité

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H360FD,H373
• pcodes: P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B - STOT RE 2
• target_organs: Liver,Kidney,Endocrine system
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves