B7283

Benserazide hydrochloride

≥98% (HPLC), solid, L-aromatic amino acid decarboxylase inhibitor

• Synonyme(s) : DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• Formule empirique (notation de Hill): C₁₀H₁₅N₃O₅ · HCl
• Numéro CAS: 14919-77-8
• Poids moléculaire : 293.70
• Numéro CE : 238-991-9
• Numéro MDL: MFCD00078571
• Code UNSPSC : 12352125
• ID de substance PubChem : 24277886
• Nomenclature NACRES : NA.77

Propriétés

• product name: Benserazide hydrochloride, ≥98% (HPLC), solid
• Source biologique: synthetic
• Pureté: ≥98% (HPLC)
• Forme: solid
• Solubilité: H₂O: 10 mg/mL
• Auteur: Roche
• Température de stockage: room temp
• Chaîne SMILES: Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
• InChI: 1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H
• Clé InChI: ULFCBIUXQQYDEI-UHFFFAOYSA-N
• Informations sur le gène: human ... DDC(1644)

Description

Description générale

Benserazide is a peripheral decarboxylase inhibitor.

Application

Benserazide has been used:

• to inhibit dopa-decarboxylase
• to induce dyskinesia
• to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases
• as a peripheral dopa decarboxylase inhibitor to treat mice

Actions biochimiques/physiologiques

Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease.

Inhibitor of L-aromatic amino acid decarboxylase.

Caractéristiques et avantages

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves