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94121

Sigma-Aldrich

Baicalin

≥99.0% (HPLC)

Synonyme(s) :

5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, Baicalein 7-O-β-D-glucuronide

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About This Item

Formule empirique (notation de Hill):
C21H18O11
Numéro CAS:
21967-41-9
Poids moléculaire :
446.36
Numéro MDL:
MFCD00134418
Code UNSPSC :
12352201
ID de substance PubChem :
329770302

Source biologique

synthetic

Pureté

≥99.0% (HPLC)

Forme

solid

Activité optique

[α]/D -83±3°, c = 1 in DMSO

Technique(s)

HPLC: suitable

Pf

202-205 °C (dec.) (lit.)

Chaîne SMILES 

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccccc4

InChI

1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1

Clé InChI

IKIIZLYTISPENI-ZFORQUDYSA-N

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Application

Baicalin, a flavonoid compound with potential therapeutic value, is used to study its anti-inflammatory and anti-oxidant properties. Baicalin is also used to study its potential as an anti-sepsis agent.

Actions biochimiques/physiologiques

Baicalin, a component of Traditional Chinese Medicine (TCM), is a flavonoid component found in several species in the genus Scutellaria. Baicalin is an inhibitor of prolyl endopeptidases.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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T B Ng et al.
Life sciences, 66(8), 709-723 (2000-02-19)
A variety of flavonoids, lignans, an alkaloid, a bisbenzyl, coumarins and terpenes isolated from Chinese herbs was tested for antioxidant activity as reflected in the ability to inhibit lipid peroxidation in rat brain and kidney homogenates and rat erythrocyte hemolysis.
Z Gao et al.
Biochimica et biophysica acta, 1472(3), 643-650 (1999-11-24)
Free radical scavenging and antioxidant activities of baicalein, baicalin, wogonin and wogonoside, the four major flavonoids in the radix of Scutellaria baicalensis Georgi, were examined in different systems. ESR results showed that baicalein and baicalin scavenged hydroxyl radical, DPPH radical
Xi-Ping Zhang et al.
World journal of gastroenterology, 13(38), 5079-5089 (2007-09-19)
To investigate the protective effects and mechanisms of Baicalin and octreotide on renal injury of rats with severe acute pancreatitis (SAP). One hundred and eighty SD rats were randomly assigned to the model group, Baicalin-treated group, octreotide-treated group and sham
Zhenhua Pei et al.
Journal of periodontology, 85(9), 1283-1290 (2014-01-31)
Periodontitis is the most common cause of tooth loss in adults. Periodontal ligament cell (PLC)-based therapy is considered one of the most promising methods in periodontal tissue regeneration. The traditional Chinese medicine baicalin has been shown to possess antimicrobial and
Miao Lin et al.
BMC complementary and alternative medicine, 14, 19-19 (2014-01-15)
Renal ischemia-reperfusion injury (IRI) increases the rates of acute kidney failure, delayed graft function, and early mortality after kidney transplantation. The pathophysiology involved includes oxidative stress, mitochondrial dysfunction, and immune-mediated injury. The anti-oxidation, anti-apoptosis, and anti-inflammation properties of baicalin, a
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