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Y0001653

Chlormadinone acetate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione, 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate, 6-Chloro-6-dehydro-17α-acetoxyprogesterone, Gestafortin, Matrol, Menstridyl

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About This Item

Formule empirique (notation de Hill):
C23H29ClO4
Numéro CAS:
302-22-7
Poids moléculaire :
404.93
Numéro Beilstein :
2633614
Numéro MDL:
MFCD00056471
Code UNSPSC :
41116107
ID de substance PubChem :
329831524
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

fraxinus chinensis

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(Cl)C4=CC(=O)CC[C@]24C

InChI

1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11-12,16-18H,5-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1

Clé InChI

QMBJSIBWORFWQT-DFXBJWIESA-N

Informations sur le gène

human ... PGR(5241)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlormadinone acetate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Review of progestogenic and related pharmacological effects of chlormadinone acetate.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

P Bouchard
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 10 Suppl 1, 7-11 (2005-12-17)
Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor. It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties. CMA acts by blocking androgen
Seiji Furuya et al.
Hinyokika kiyo. Acta urologica Japonica, 51(3), 159-164 (2005-04-28)
Between August 1985 and March 2004, we performed transurethral resection of the prostate (TURP) in 18 patients with benign prostatic hyperplasia (BPH) whose prostatic volume was larger than 100 ml. We divided the patients into two groups. Group A consisted
Aurora Guerra-Tapia et al.
American journal of clinical dermatology, 12 Suppl 1, 3-11 (2011-09-16)
Acne vulgaris, hirsutism, seborrhea and female pattern hair loss (FPHL) are common disorders of the pilosebaceous unit (PSU). In some women with hyperandrogenemia, an excess of androgens at the PSU can lead to the development of these dermatological manifestations. These
Hideyuki Iwahata et al.
Journal of assisted reproduction and genetics, 32(4), 521-526 (2015-01-27)
Closed vitrification poses a risk of adversely affecting embryo development, while it may minimize the risk of contamination. We assessed the effects of closed-system human embryo vitrification on fetal development after implantation, neonatal outcome, and clinical safety. This was a

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