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I0330000

Iopanoic acid

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-(3-Amino-2,4,6-triiodobenzyl)butyric acid, 3-(3-Amino-2,4,6-triiodophenyl)-2-ethylpropanoic acid, Iodopanoic acid

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About This Item

Formule empirique (notation de Hill):
C11H12I3NO2
Numéro CAS:
96-83-3
Poids moléculaire :
570.93
Numéro MDL:
MFCD00038687
Code UNSPSC :
41116107
ID de substance PubChem :
329815308
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

iopanoic acid

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O=C(O)C(CC)CC1=C(I)C(N)=C(I)C=C1I

InChI

1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)

Clé InChI

OIRFJRBSRORBCM-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Iopanoic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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A Colantuoni et al.
American journal of physiology. Heart and circulatory physiology, 288(4), H1931-H1936 (2004-12-04)
The aim of the present study was to assess the effects of topically applied triiodothyronine (T(3)) and thyroxine (T(4)) on the arterioles of hamster cheek pouch microcirculation in vivo. Microvessels were visualized using a fluorescent microscopy technique. Topical application of
Joshua D Safer et al.
Thyroid : official journal of the American Thyroid Association, 19(2), 181-185 (2009-02-05)
Although cutaneous manifestations associated with thyroid dysfunction are classic, the potential for thyroid hormone or its antagonists to treat dermatological disease has not been explored with rigor. The predominant circulating thyroid hormone is the pro-hormone, thyroxine (T(4)). Skin, like many
C S Bal et al.
The Journal of clinical endocrinology and metabolism, 90(12), 6536-6540 (2005-09-29)
Telepaque [iopanoic acid (IA)] is believed to rapidly ameliorate hyperthyroidism; however, it may preclude subsequent 131I therapy, possibly delaying it for several months. Our objective was to see how early patients, made euthyroid with Telepaque, can be treated with 131I
Fernando Lizcano et al.
Clinical and experimental pharmacology & physiology, 35(9), 1085-1090 (2008-05-29)
To investigate the effects of iopanoic acid (IA) and carbimazole on increased activity of the hypothalamic-pituitary-adrenal (HPA) axis in hyperthyroidism, we studied 14 women with hyperthyroidism caused by Graves' disease (n + 11) or toxic multinodular goitre (n + 3)
Rossella Monteforte et al.
The Journal of experimental biology, 211(Pt 4), 606-612 (2008-02-05)
The secretory activity of the Harderian gland (HG) is influenced by both exogenous (such as light and temperature) and endogenous (such as prolactin, thyroid hormones and steroid hormones) factors, which vary among species. In the present study, the effects of
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