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Mettler-Toledo Calibration substance ME 51143091, Saccharin

traceable to primary standards (LGC)

Synonyme(s) :

Saccharin, 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, 2-Sulfobenzoic acid imide, o-Benzoic sulfimide

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About This Item

Formule empirique (notation de Hill):
C7H5NO3S
Numéro CAS:
Poids moléculaire :
183.18
Numéro Beilstein :
6888
Numéro CE :
Numéro MDL:
Code UNSPSC :
20121904
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard
traceable to primary standards (LGC)

Niveau de qualité

Durée de conservation

limited shelf life, expiry date on the label

Pf

226-229 °C (lit.)

Application(s)

food and beverages
pharmaceutical

Format

neat

Chaîne SMILES 

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

Clé InChI

CVHZOJJKTDOEJC-UHFFFAOYSA-N

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Description générale

Mettler-Toledo calibration substance ME 51143091, saccharin is an analytical standard, designed for the routine calibration of Mettler-Toledo melting point instrument. Its value is an average of 6 to 12 measurements with a Mettler-Toledo MP90 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method as per European Pharmacopeia (2.2.14.)

Application

Saccharin Mettler-Toledo calibration substance ME 51143091 is a melting point calibration standard used to calibrate Mettler-Toledo mp instruments.

Actions biochimiques/physiologiques

A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.

Caractéristiques et avantages

  • Traceable to a primary standard from LGC, London
  • Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
  • Available with certificates of analysis and safety data sheet
  • A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
  • Uncertainty of measurement up to ± 0.3 °C

Informations légales

Mettler-Toledo is a registered trademark of Mettler-Toledo, Inc.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Molecular pharmaceutics, 9(9), 2605-2612 (2012-08-08)
Cocrystals constitute an important class of pharmaceutical solids for their remarkable ability to modulate solubility and pH dependence of water insoluble drugs. Here we show how cocrystals of indomethacin-saccharin (IND-SAC) and carbamazepine-saccharin (CBZ-SAC) enhance solubility and impart a pH-sensitivity different
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A process for the regioselective amination of unsymmetrical 3,5-substituted pyridine N-oxides has been developed utilizing cheap, readily available saccharin as an ammonium surrogate. High conversions of the corresponding saccharin adducts have been achieved under mild reaction conditions. In situ deprotection
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