05238

Erythromycin-A-enolether

analytical standard

• Formule empirique (notation de Hill) : C₃₇H₆₅NO₁₂
• Numéro CAS: 33396-29-1
• Poids moléculaire : 715.91
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Essai: ≥95% (HPLC)
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• Chaîne SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H](C3O)N(C)C)[C@@]4(C)CC(C)=C(O4)[C@H](C)[C@@H](O)[C@]1(C)O
• InChI: 1S/C37H65NO12/c1-14-25-37(10,43)30(40)20(4)28-18(2)16-36(9,50-28)32(49-34-27(39)24(38(11)12)15-19(3)45-34)21(5)29(22(6)33(42)47-25)48-26-17-35(8,44-13)31(41)23(7)46-26/h19-27,29-32,34,39-41,43H,14-17H2,1-13H3/t19-,20+,21+,22-,23+,24+,25-,26+,27-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
• Clé InChI: JFVYXJKGJMUGRG-KJPZRSJGSA-N

Description

Description générale

Erythromycin A enol ether (EAEN) is an acidic degradation product of erythromycin A (EA) which is grouped under the macrolide antibiotic class of compounds.[1]

Application

EAEN has been used for the analysis of EAEN as degradation product of EA in honey by ultra-performance liquid chromatography equipped with tandem quadrupole mass spectrometer (UPLC-MS/MS) with positive electrospray ionisation (ESI) operating on multiple reaction monitoring (MRM) mode[2] and in rat′s blood plasma, serum and human urine by high performance liquid chromatography-coulometric assay. It may be used as a reference standard for the detection of EAEN in erythromycin fractions by isocratic LC with evaporative light scattering detection (ELSD) and ion trap MS[3] and in commercial erythromycin samples by LC-MS/MS.[4]

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)