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Key Documents

MAB5260Z

Sigma-Aldrich

Anti-Nerve Growth Factor Antibody, clone 27/21, azide free

clone 27/21, Chemicon®, from mouse

Synonyme(s) :

NGF, MAB5260

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

27/21, monoclonal

Espèces réactives

human, rat, bovine, mouse

Conditionnement

antibody small pack of 25 μg

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
neutralization: suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NTF3(4908)

Spécificité

Specifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form.

Immunogène

2.5 S form of mouse NGF.

Application

Detect Nerve Growth Factor using this Anti-Nerve Growth Factor Antibody, clone 27/21, azide free validated for use in ELISA, NEUT.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
The antibody is used for the neutralization of NGF in cell culture systems. Furthermore the antibody is used to immunosympathectomy.

Optimal working dilutions must be determined by end user.

Liaison

Replaces: 04-1119

Forme physique

Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
Protein A purified

Stockage et stabilité

Maintain for 6 months at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
Brain tissue

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

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Aalto, AP; Sarin, LP; van Dijk, AA; Saarma, M; Poranen, MM; Arumae, U; Bamford, DH
RNA null
M Jakobson et al.
Cell death & disease, 4, e777-e777 (2013-08-24)
N-Bak is a neuron-specific BH3-only splice variant of pro-apoptotic Bcl-2 family member Bak. We have shown that its mRNA is stable in the neurons, whereas the protein cannot be detected by antibodies, suggesting a strong translational arrest of the mRNA.
Mikk Raba et al.
Frontiers in cellular neuroscience, 10, 66-66 (2016-03-26)
Postnatal maturation of the neurons whose main phenotype and basic synaptic contacts are already established includes neuronal growth, refinement of synaptic contacts, final steps of differentiation, programmed cell death period (PCD) etc. In the sympathetic neurons, postnatal maturation includes permanent
Patricia Cassina et al.
Journal of neurochemistry, 93(1), 38-46 (2005-03-19)
Fibroblast growth factor-1 (FGF1 or acidic FGF) is highly expressed in motor neurons. FGF-1 is released from cells by oxidative stress, which might occur from SOD-1 aberrant function in amyotrophic lateral sclerosis (ALS). Although FGF-1 is known to be neuroprotective
E Stener-Victorin et al.
Obesity science & practice, 2(4), 426-435 (2017-01-17)
Insulin sensitivity is ~40% lower in women with polycystic ovary syndrome (PCOS) than in controls. We tested the hypothesis that 5 weeks of electroacupuncture treatment improves glucose regulation and androgen levels in overweight/obese women with PCOS. Seventeen women with PCOS, aged

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