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MAB396

Sigma-Aldrich

Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

clone 3A11, Chemicon®, from mouse

Synonyme(s) :

GluR2/4

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

3A11, monoclonal

Espèces réactives

monkey, human, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable
western blot: suitable

Isotype

IgG2a

Numéro d'accès NCBI

NM_000839.2

Numéro d'accès UniProt

Q14416
Q14833

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GRIA2(2891)
rat ... Gria2(29627)
rhesus monkey ... Gria2(574344)

Spécificité

Glutamate Receptor 2 (GluR2) by Western blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.

Immunogène

Recombinant fusion protein TrpE-GluR2

Application

Detect Glutamate Receptor 2 & 4 using this Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 validated for use in ELISA, IC, IH, IP, RIA & WB.
Immunohistochemistry on 4% paraformaldehyde fixed

tissue: 1:500-1,000

Immunocytochemistry

ELISA

RIA

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Forme physique

Format: Purified
Purified immunoglobulin. Liquid in PBS, no preservative.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up 12 months. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Sheng Chen et al.
Journal of neuroscience research, 81(4), 522-529 (2005-06-11)
Lipid rafts are specialized plasma membrane microdomains enriched in cholesterol and sphingolipids that serve as major assembly and sorting platforms for signal transduction complexes. Constitutively expressed heat shock proteins Hsp90, Hsc70, Hsp60, and Hsp40 and a range of neurotransmitter receptors
Dannis G van Vuurden et al.
PloS one, 4(6), e5953-e5953 (2009-06-19)
Glioblastoma multiforme (GBM) cells secrete large amounts of glutamate that can trigger AMPA-type glutamate receptors (AMPARs). This commonly results in Na(+) and Ca(2+)-permeability and thereby in excitotoxic cell death of the surrounding neurons. Here we investigated how the GBM cells
Shoko Shimizu et al.
Glia, 62(5), 709-724 (2014-02-01)
Recent studies have shown changes in myelin genes and alterations in white matter structure in a wide range of psychiatric disorders. Here we report that DBZ, a central nervous system (CNS)-specific member of the DISC1 interactome, positively regulates the oligodendrocyte
Jureepon Roboon et al.
Frontiers in cellular neuroscience, 13, 258-258 (2019-06-28)
CD38 is an enzyme that catalyzes the synthesis of cyclic adenosine diphosphate-ribose from nicotinamide adenine dinucleotide (NAD+). We recently reported that this molecule regulates the maturation and differentiation of glial cells such as astrocytes and oligodendrocytes (OLs) in the developing
Ester Orav et al.
Molecular neurobiology, 56(11), 7473-7489 (2019-05-03)
Kainate type ionotropic glutamate receptors (KARs) are expressed in hippocampal interneurons and regulate interneuron excitability and GABAergic transmission. Neuropilin tolloid-like proteins (NETO1 and NETO2) act as KAR auxiliary subunits; however, their significance for various functions of KARs in GABAergic interneurons
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